Cheek Swap Test Kit
Methylation is a fundamental biochemical process involved in gene regulation, detoxification, neurotransmitter production, hormone metabolism and cardiovascular health. Small variations in certain genes can influence how efficiently this process occurs within the body.
The Genetic Methylation Test analyses key genetic variants involved in the methylation pathway using a simple cheek swab sample collected at home.
By identifying single nucleotide polymorphisms (SNPs) within important methylation-related genes, this test helps reveal how effectively your body may process nutrients such as folate, vitamin B12 and other cofactors required for optimal methylation.
Understanding these genetic patterns can help guide personalised nutrition, supplementation and lifestyle strategies aimed at supporting detoxification pathways, neurological health and metabolic balance.
Genetic Methylation Test
This test evaluates several genes involved in the methylation cycle and related metabolic pathways.
Methylation Cycle Genes
These genes influence how efficiently your body performs methylation reactions that regulate DNA expression and biochemical pathways.
Markers may include:
• MTHFR
• MTR
• MTRR
• AHCY
• BHMTThese genes help regulate the conversion of folate and the recycling of homocysteine into methionine, a key step in the methylation cycle.
Neurotransmitter Regulation Genes
Certain genes influence how methylation affects brain chemistry and neurotransmitter metabolism.
Examples may include:
• COMT
Variants in these genes can influence how neurotransmitters such as dopamine and norepinephrine are processed in the body.
Detoxification and Metabolic Pathways
Methylation genes also interact with pathways involved in:
• Detoxification processes
• Hormone metabolism
• Nutrient utilisation
• Cardiovascular healthUnderstanding these pathways can provide insight into how genetic differences may influence overall health.
This analysis may provide insight into:
• Variations in methylation pathway efficiency
• Genetic patterns influencing folate and B-vitamin metabolism
• Factors that may affect detoxification pathways
• Genetic influences on neurotransmitter metabolism
• Patterns that may influence cardiovascular or metabolic healthUnderstanding these genetic patterns can help guide targeted strategies aimed at supporting methylation pathways and metabolic function.
This test may be beneficial for individuals who:
• Want insight into their methylation genetics
• Experience fatigue or low energy
• Have concerns related to detoxification or nutrient metabolism
• Experience mood or neurological symptoms
• Want to personalise nutrition and supplementation strategiesIt may also be useful for individuals interested in nutrigenomics and personalised health optimisation.
Once your laboratory results are available, you will be required to book a results consultation to review your report.
During this session, your genetic results are interpreted within a clinical context and translated into practical health strategies.
Your consultation may include discussion around:
• Nutritional strategies to support methylation pathways
• Targeted supplementation where appropriate
• Lifestyle factors influencing gene expression
• Strategies to support detoxification and metabolic healthTo ensure accurate results, please follow these preparation guidelines:
• Collect a cheek swab sample using the kit provided
• Avoid eating or drinking for approximately one hour before sample collection
• Follow the instructions included with the testing kit for proper sample collection
• Return the sample according to the shipping instructions providedBecause this test analyses genetic information, results are not influenced by illness, diet or medications at the time of testing.
Your results report provides insight into genetic variants within key methylation pathway genes.
The report typically highlights:
• Variants within methylation-related genes such as MTHFR and related pathways
• Genetic patterns influencing nutrient metabolism
• Insights into detoxification and metabolic pathways
• Personalised recommendations to support methylation functionInterpreting these results within a clinical consultation allows personalised strategies to be developed to support nutrient metabolism, detoxification pathways and overall health optimisation.
Many people take supplements without truly understanding what their body needs. While some nutrients can be helpful, taking supplements without proper assessment may mean addressing the wrong problem or missing important underlying factors.
Functional testing allows us to move beyond guesswork and instead use objective data to guide personalised health strategies.
Testing can help identify:
• Nutrient deficiencies or imbalances
• Environmental exposures that may impact health
• Microbial imbalances within the gut
• Genetic variations that influence metabolism and cellular processes
• Biological patterns that may be contributing to symptomsRather than taking a generalised approach, testing provides information that allows recommendations to be tailored to your individual physiology.
This helps ensure that nutritional strategies, supplementation and lifestyle interventions are targeted, appropriate and aligned with your specific health needs.
For this reason, all testing offered through the clinic is reviewed within a clinical consultation, where results are interpreted and translated into practical, personalised recommendations.
Functional health testing can provide valuable insights into how the body is functioning. However, interpreting these results correctly requires clinical context.
Laboratory reports often present large amounts of technical data, and results may fall within reference ranges while still indicating patterns that are relevant to your health.
Working with a practitioner ensures that your results are reviewed in relation to your:
• Symptoms and health history
• Current diet and lifestyle factors
• Medication or supplement use
• Environmental exposures
• Overall health goalsRather than looking at individual markers in isolation, a practitioner assesses patterns across multiple systems to better understand what may be influencing your health.
During your results consultation, findings from your test are translated into clear and practical recommendations, which may include targeted nutrition strategies, lifestyle adjustments and appropriate supplementation where required.
This personalised approach helps ensure that testing leads to meaningful, actionable changes that support long-term health outcomes.
